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Results for "

collagen 3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) Adenosine Receptor (1) Amyloid-β (1) Angiotensin Receptor (3) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (1) Apoptosis (24) Autophagy (7) Bacterial (3) Biochemical Assay Reagents (4) c-Fms (1) Calcium Channel (17) Caspase (1) CaSR (2) Cathepsin (2) CCR (1) CDK (1) COX (2) Cuproptosis (1) CXCR (1) Discoidin Domain Receptor (1) DNA/RNA Synthesis (3) DYRK (1) EBI2/GPR183 (1) Endogenous Metabolite (22) ERK (1) Fluorescent Dye (1) Fungal (1) Glycoprotein VI (3) GSK-3 (1) HIF/HIF Prolyl-Hydroxylase (3) Histone Methyltransferase (1) HIV (3) HSP (1) HSV (1) Influenza Virus (1) Integrin (10) IRAK (3) Isotope-Labeled Compounds (3) JAK (3) JNK (1) Lipoxygenase (1) LPL Receptor (1) MDM-2/p53 (1) MMP (14) Monoamine Oxidase (3) Neprilysin (1) NF-κB (3) NO Synthase (3) P2Y Receptor (3) p38 MAPK (3) Parasite (4) Phosphatase (6) Phosphodiesterase (PDE) (2) PI3K (2) PKA (5) PKC (5) Platelet-activating Factor Receptor (PAFR) (1) Prostaglandin Receptor (3) Protease Activated Receptor (PAR) (3) PTHR (1) Reactive Oxygen Species (17) ROCK (5) Ser/Thr Protease (1) Sodium Channel (3) Src (1) Syk (1) TAM Receptor (1) TGF-beta/Smad (4) TGF-β Receptor (3) Thrombin (1) TNF Receptor (1) Toll-like Receptor (TLR) (3) VSV (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (47) Cardiovascular Disease (34) Endocrinology (6) Infection (10) Inflammation/Immunology (68) Metabolic Disease (33) Neurological Disease (8)
Click Chemistry:	Alkynes (1)

170

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Collagen proline hydroxylase inhibitor	Others	Cancer
Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor; useful for antifibroproliferative agents.

Collagen-IN-1	Others	Cardiovascular Disease
Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on *collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC₅₀ value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen*-IN-1 has the potential for platelet-related thrombosis diseases research .

Collagen Type II Fragment	Biochemical Assay Reagents	Inflammation/Immunology
Collagen Type II Fragment is an anti-inflammatory peptide that potently inhibits collagen-induced arthritis (CIA) in mice. Collagen Type II Fragment can be used for research on inflammation and immunity .

Collagen proline hydroxylase inhibitor-1	Others	Cancer
Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents.

Methacrylated Type I collagen Col1MA	Biochemical Assay Reagents	Others
Methacrylated Type I collagen (Col1MA) is a methacrylated tissue engineering scaffold material. Methacrylated Type I collagen retains the essential properties of natural collagen, including spontaneous fiber self-assembly and enzymatic biodegradability. Methacrylated Type I collagen is capable of self-assembly into fibrous hydrogels, intrinsic support of tissue cells through bioactive adhesion sites, and its biodegradability. After photo-cross-linking CMA, the cell viability of encapsulated mesenchymal stem cells was protected .

Col003 2 Publications Verification	HSP	Inflammation/Immunology
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC₅₀=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis

6-Methoxydihydroavicine	Platelet-activating Factor Receptor (PAFR)	Cancer
6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro .

N-Acetyldopamine dimmers A	Others	Inflammation/Immunology
N-Acetyldopamine dimmers A (Compound (+)-2) can be isolated from the cast-off shell of the cicada of Cryptotympana sp. N-Acetyldopamine dimmers A increases collagen and α-SMA expression .

α2β1 Integrin Ligand Peptide TFA 2 Publications Verification DGEA peptide TFA	Integrin	Others
α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .

cis-4-Hydroxy-L-proline	Endogenous Metabolite	Metabolic Disease Cancer
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors ^[3] .

Cyclomulberrin	Others	Cardiovascular Disease
Cyclomulberrin is a extended flavonoid that shows inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation, with IC₅₀ value of 128.2 μM .

FAP-PI3KI1	PI3K	Cancer
FAP-PI3KI1 is a fibroblast-activated protein (FAP)-targeted *PI3K* inhibitor that selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells and effectively inhibits collagen synthesis and reduces collagen deposition .

Curcolone	Others	Cardiovascular Disease
Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .

Safironil	Others	Inflammation/Immunology
Safironil is an antifibrotic compound. Safironil is a competitive inhibitor of collagen protein synthesis. Safironil reduces liver fibrogenesis by inhibiting HSC activation .

Pyridinoline	Endogenous Metabolite	Others
Pyridinoline, a fluorescent material, is a bone resorption biomarker. Pyridinoline also is a type crosslink of collagen .

Galactosylhydroxylysine	Endogenous Metabolite	Metabolic Disease
Galactosylhydroxylysine is a component of bone collagen produced by post-translational glycosylation of hydroxylysine. Galactosylhydroxylysine is released during bone resorption and has been shown to be elevated in metabolic bone loss .

Galactosylhydroxylysine hydrochloride	Endogenous Metabolite	Metabolic Disease
Galactosylhydroxylysine hydrochloride is a component of bone collagen produced by post-translational glycosylation of hydroxylysine. Galactosylhydroxylysine hydrochloride is released during bone resorption and has been shown to be elevated in metabolic bone loss .

19-epi-Scholaricine	Reactive Oxygen Species	Inflammation/Immunology
19-epi-Scholaricine is an orally active indole alkaloid that downregulates the expression of collagen fibrosis and increases superoxide dismutase (SOD) activities .

Dopamine acrylamide	Others	Others
Dopamine acrylamide, a polyphenol derivative, can cross-link collagen mainly via noncovalent bonding under acidic-non-oxidized conditions .

L-hydroxylysine dihydrochloride (2S,5R)-5-Hydroxylysine dihydrochloride	Endogenous Metabolite	Others
L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues .

PythiDC	MMP	Inflammation/Immunology
PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC₅₀ value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents .

GPVI antagonist 2	Glycoprotein VI	Cardiovascular Disease
GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC₅₀ values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent .

GPVI antagonist 3	Glycoprotein VI	Cardiovascular Disease
GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC₅₀ values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent .

TP0556351	MMP	Inflammation/Immunology
TP0556351 is a potent and selective matrix metalloproteinase-2 (MMP2) inhibitor with an IC₅₀ value of 0.2 nM. TP0556351 reduces the amount of collagen in the lungs of a Bleomycin-induced pulmonary fibrosis mouse model. TP0556351 can be used for researching idiopathic pulmonary fibrosis (IPF) .

MAHMA NONOate	Endogenous Metabolite NO Synthase	Cardiovascular Disease
MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP .

TGFβ-IN-2	TGF-beta/Smad	Inflammation/Immunology
TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC₅₀ of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration .

Traumatic Acid	Reactive Oxygen Species Apoptosis	Inflammation/Immunology
Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis .

Light green SF yellowish Acid Green 5	Fluorescent Dye	Others
Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains .

ATX inhibitor 18	Phosphodiesterase (PDE)	Cardiovascular Disease
ATX inhibitor 18 is a potent ATX inhibitor with an IC₅₀ value of 24.2 nM. ATX inhibitor 18 shows antiproliferative activity and anti-fibrosis activity. ATX inhibitor 18 suppresses collagen deposition in TGF-β-mediated cardiac fibrosis .

Obtustatin	Integrin	Cancer
Obtustatin is a non-RGD disintegrin of 41 residues. Obtustatin can be isolated from Vipera lebetina obtusa venom. Obtustatin is a potent and selective inhibitor of the adhesion of integrin α1β1 to collagen IV. Obtustatin inhibits angiogenesis, and can be used for research of cancer .

Isosaponarin	TGF-β Receptor	Others
Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin increases collagen synthesis, caused by up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production .

Flaccidoside II	Apoptosis	Inflammation/Immunology
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .

Vapiprost hydrochloride	Prostaglandin Receptor	Others
Vapiprost hydrochloride is a thromboxane A2 receptor antagonist. Vapiprost inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC₅₀ of less than 2.1×10 ^-8 M .

Trequinsin hydrochloride HL 725	Phosphodiesterase (PDE)	Metabolic Disease
Trequinsin hydrochloride (HL 725) is an extremely potent inhibitor of platelet CAMP phosphodiesterase (PDE), with an IC₅₀ of 0.25 nM. Trequinsin hydrochloride (HL 725) is an extremely potent inhibitor of the aggregation of human platelets induced in vitro by ADP, collagen, thrombin and epinephrine ^[3].

PAPA NONOate	Endogenous Metabolite	Endocrinology
PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site ^[3].

Direct Red 80 Sirius Red	Amyloid-β	Others
Direct Red 80 (Sirius Red) is a polyazo dye used principally in staining methods for collagen and amyloid. Direct Red 80 does not release benzidine upon degradation and is safer than many traditional direct dyes .

Ethyl 3,4-dihydroxybenzoate Ethyl protocatechuate	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species NO Synthase Autophagy Apoptosis	Metabolic Disease Cancer
Ethyl 3,4-dihydroxybenzoate (Ethyl protocatechuate), an antioxidant, is a prolyl-hydroxylase inhibitor found in the testa of peanut seeds. Ethyl 3,4-dihydroxybenzoate protects myocardium by activating NO synthase and generating mitochondrial ROS. Ethyl 3,4-dihydroxybenzoate induces cell autophagy and apoptosis in ESCC cells. Ethyl 3,4-dihydroxybenzoate is a collagen synthesis inhibitor and has a bone protecting-effect ^[3] .

Aristolactam A IIIa Aristololactam A IIIa; Sch 546909	DYRK	Cardiovascular Disease Cancer
Aristolactam A IIIa (Sch 546909) is an aristolactam-type alkaloid that can be isolated from Glycosmis chlorosperma. Aristolactam A IIIa is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells .

Halofuginone 5+ Cited Publications RU-19110	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity ^[3] . Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

L-006235 L-235	Cathepsin	Metabolic Disease
L-006235 (L-235) is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC₅₀ of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (K_i=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (K_i=1, 6, and 47 μM, respectively). L-006235 can reduce collagen degradation and prevent bone loss .

Halofuginone hydrobromide 5+ Cited Publications RU-19110 hydrobromide	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity ^[3] . Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

Halofuginone hydrochloride RU-19110 hydrochloride	Calcium Channel DNA/RNA Synthesis Parasite Sodium Channel TGF-beta/Smad	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects ^[3] .

PLN-1474	Integrin	Inflammation/Immunology
PLN-1474 (compound 1) is an orally active and selective ανβ1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder.

Quin C1	Others	Inflammation/Immunology
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury .

L-Ascorbic acid 35+ Cited Publications L-Ascorbate; Vitamin C	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

AF299	Others	Cardiovascular Disease
AF299 can reduce collagen-related peptide-induced platelet Ca ²⁺ rises and collagen-induced platelet aggregation. AF299 can be used for research of antiplatelet research .

Cat. No.	Product Name	Type

HY-126367

Light green SF yellowish Acid Green 5	Dyes
Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains .

HY-B0166GL

L-Ascorbic acid (GMP Like)

L-Ascorbate (GMP Like); Vitamin C (GMP Like)

Fluorescent Dye

L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

Cat. No.	Product Name	Type

HY-NP003

Bovine Type II Collagen collagen, Type II, Immunization Grade	Native Proteins
Type II collagen II is a protein used to treat osteoarthritis. Type II collagen shows significant efficacy in improving the pain and inflammation of collagen induced arthritis in mice .

HY-P2738

Collagens	Native Proteins
Collagens are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue .

HY-NP010

Collagen, rat tail

Native Proteins

Collagen, rat tail is a kind of collagen extracted from rat tail tendon tissue, which is often used as an attachment substrate for cell culture .

HY-158225

Methacrylated Type I collagen

Col1MA

3D Bioprintig

Methacrylated Type I collagen (Col1MA) is a methacrylated tissue engineering scaffold material. Methacrylated Type I collagen retains the essential properties of natural collagen, including spontaneous fiber self-assembly and enzymatic biodegradability. Methacrylated Type I collagen is capable of self-assembly into fibrous hydrogels, intrinsic support of tissue cells through bioactive adhesion sites, and its biodegradability. After photo-cross-linking CMA, the cell viability of encapsulated mesenchymal stem cells was protected .

HY-P2913

Vitronectin	Native Proteins
Vitronectin is a multifunctional glycoprotein present in blood and in the extracellular matrix. Vitronectin binds glycosaminoglycans, collagen, plasminogen and the urokinase-receptor. Vitronectin also stabilizes the inhibitory conformation of plasminogen activation inhibitor-1. Vitronectin can be used for researching wound healing and in tumorprogression .

HY-B0166GL

L-Ascorbic acid (GMP Like)

L-Ascorbate (GMP Like); Vitamin C (GMP Like)

Biochemical Assay Reagents

HY-P3160

Fibronectin 1 Publications Verification	Native Proteins
Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .

HY-158226

Elastin Methacrylated

ElaMA

3D Bioprintig

Elastin Methacrylated (ElaMA) elastin recruits and modulates innate immune cells and accelerates angiogenesis at the wound site, thereby improving wound regeneration. Elastin Methacrylated attracts large numbers of neutrophils and primarily M2 macrophages to the wound and induces their penetration into the hydrogel. Elastin Methacrylated has excellent immunomodulatory effects, leading to superior angiogenesis, collagen deposition and dermal regeneration .

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate

2-Phospho-L-ascorbic acid magnesium hydrate

Biochemical Assay Reagents

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation ^[3].

Cat. No.	Product Name	Target	Research Area

HY-P1912

Alpha 1(I) Collagen (614-639), human

Peptides Endocrinology

Alpha 1(I) Collagen (614-639), human is a peptide fragment of alpha-1 type I collagen.

HY-P3524

GRGESP	Peptides	Others
GRGESP is a collagen gel contraction inhibitor. GRGESP inhibits the spreading of human fibroblasts inside collagen gels and markedly decreased gel contraction. GRGDSP can be used for the research of connective tissue morphogenesis .

HY-P1868A

α2β1 Integrin Ligand Peptide TFA 2 Publications Verification DGEA peptide TFA	Integrin	Others
α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .

HY-P3163

Hexapeptide-9	Peptides	Others
Hexapeptide-9 is a collagen peptide, with anti-aging activity. Hexapeptide-9 is commonly used as the ingredient in skin care products for improving the appearance of the skin .

HY-P5003

Collagen Type II Fragment	Biochemical Assay Reagents	Inflammation/Immunology
Collagen Type II Fragment is an anti-inflammatory peptide that potently inhibits collagen-induced arthritis (CIA) in mice. Collagen Type II Fragment can be used for research on inflammation and immunity .

HY-P5263

YYRADDA	Peptides	Others
YYRADDA is a polypeptide. YYRADDA stimulates the growth of collagen in the extracellular matrix of the skin. YYRADDA improves the appearance of the skin and promotes the healing of damaged skin .

HY-P1408

Obtustatin	Integrin	Cancer
Obtustatin is a non-RGD disintegrin of 41 residues. Obtustatin can be isolated from Vipera lebetina obtusa venom. Obtustatin is a potent and selective inhibitor of the adhesion of integrin α1β1 to collagen IV. Obtustatin inhibits angiogenesis, and can be used for research of cancer .

HY-P3121

Caprooyl-tetrapeptide-3 acetate	Peptides	Metabolic Disease
Caprooyl-tetrapeptide-3 acetate is used for fine lines and wrinkle reduction. Caprooyl-tetrapeptide-3 acetate stimulates the expression of collagen VII and laminin-5 in a model of corticoid-induced skin ageing .

HY-P0170

TB500 1 Publications Verification	Peptides	Metabolic Disease
TB500 is a synthetic version of an active region of thymosin β₄. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation .

HY-W129161

Acetyl tetrapeptide-3	Peptides	Metabolic Disease
Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and Acetyl tetrapeptide-3, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring .

HY-P4231

H-Gly-Ala-Hyp-OH

Peptides Others

H-Gly-Ala-Hyp-OH is a collagen tripeptide fragment .
HY-W016887

H-Gly-Pro-OH

Endogenous Metabolite Metabolic Disease

H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

HY-P4550

H-Hyp-Gly-OH	Endogenous Metabolite	Metabolic Disease
H-Hyp-Gly-OH is a dipeptide containing hydroxyproline and glycine. H-Hyp-Gly-OH promotes the growth of mouse primary fibroblasts on collagen gel. H-Hyp-Gly-OH has potential applications in improving skin by ingesting hydrolyzed collagen. H-Hyp-Gly-OH can be used for metabolic research .

HY-P4309

H-Gly-Tyr-Gly-OH

Peptides Others

H-Gly-Tyr-Gly-OH, a tyrosine tripeptide, can be found in structural and transport proteins such as collagen and ion channels .

HY-P5081

Endotrophin (Mus musculus)	Peptides	Inflammation/Immunology
Endotrophin (Mus musculus) is a cleavage product of collagen 6 (Col6). Endotrophin upregulation of both profibrotic and proinflammatory genes .

HY-P4812

Prepro-von Willebrand factor (641-650) (bovine)	Peptides	Metabolic Disease
Prepro-von Willebrand factor (641-650) (bovine) is a fragment of Prepro-von Willebrand factor, which binds to type I collagen .

HY-P0284

C-telopeptide	Peptides	Inflammation/Immunology
C-telopeptide, a cross-linked peptide of type I collagen, is released during bone resorption and has been correlated with bone mineral density (BMD).

HY-P5224

Lipospondin

Peptides Others

Lipospondin is a bioactive peptide with anti-wrinkl effect and has been reported used as a cosmetic ingredient .

HY-P5237

Tetrapeptide-4	Peptides	Others
Tetrapeptide-4 is a peptide ingredient commonly used in skin care products to reduce wrinkles, strengthen collagen, elastin and fibronectin, and possess powerful anti-aging properties .

HY-P1868

α2β1 Integrin Ligand Peptide DGEA peptide	Integrin	Infection
α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors .

HY-P10184

CD36 Peptide P (93-110), Cys conjugated	Peptides	Inflammation/Immunology
CD36 Peptide P (93-110), Cys conjugated is a Cys labelled CD36 Peptide, and can block binding of CD36 to immobilized thrombospondin and partially inhibited collagen-induced platelet aggregation .

HY-P10136

IA9 human TREM-2 182-190	Peptides	Inflammation/Immunology
IA9 (human TREM-2 182-190) is a TREM-2 inhibitor , and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model .

HY-P10136A

IA9 TFA human TREM-2 182-190 TFA	Peptides	Inflammation/Immunology
IA9 TFA (human TREM-2 182-190 TFA) is a TREM-2 inhibitor , and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model .

HY-P4684

Osteostatin PTHrP (107–111)	PTHR
Osteostatin, a fragment of parathyroid hormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research ^[3] .

HY-P1408A

Obtustatin triacetate	Integrin	Cancer
Obtustatin triacetate is a 41-residue non-RGD disintegrin. Obtustatin triacetate can be isolated from the venom of Vipera lebetina obtusa. Obtustatin triacetate is a potent and selective inhibitor of integrin α1β1 adhesion to type IV collagen. Obtustatin triacetate inhibits angiogenesis and may be used in cancer research .

HY-P4486

H-Pro-Gly-Pro-OH	Peptides	Others
H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .

HY-P3459

Tet-213

Bacterial Infection

Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair .

HY-P0045

Palmitoyl pentapeptide 4 Matrixyl; Palmitoyl pentapeptide 3; Matrixyl (Palmitoyl Pentapeptide)	Peptides	Others
Palmitoyl pentapeptide 4 (Matrixyl; Palmitoyl pentapeptide 3; Matrixyl (Palmitoyl Pentapeptide) is a bioactive peptide with anti-ageing effect and has been reported used as a cosmetic ingredient ^[1]

HY-P5242

Tripeptide-10 citrulline

T10-C
Peptides Others

Tripeptide-10 citrulline (T10-C) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
HY-P5244

Tripeptide-32

Apoptosis Caspase Metabolic Disease

Tripeptide-32isa bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-P1181

Pam2CSK4	Toll-like Receptor (TLR)	Inflammation/Immunology
Pam2CSK4, a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-κB/BTK-dependent manner. Pam2CSK4 also activates iNOS expression and NO production in mouse macrophages ^[3].

HY-P1181A

Pam2CSK4 TFA	Toll-like Receptor (TLR)	Inflammation/Immunology
Pam2CSK4 (TFA), a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 (TFA) promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-κB/BTK-dependent manner. Pam2CSK4 (TFA) also activates iNOS expression and NO production in mouse macrophages ^[3].

HY-P3459A

Tet-213 TFA

Bacterial Infection

Tet-213 TFA is a antimicrobial peptide. Tet-213 TFA has broad spectrum antibacterial activity. Tet-213 TFA can promote infected wound repair .
HY-P3164

Acetyl tetrapeptide-9

AcTP1
Peptides Others

Caprooyl-tetrapeptide-9 (AcTP1) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
HY-P5261

SA1-III

KP1
Peptides Metabolic Disease

SA1-III(KP1) is a bioactive peptide withanti-agingeffect and has been reported used as a cosmetic ingredient .

HY-P5268

Palmitoyl hexapeptide-14 Palmitoyl hexapeptide-6	Peptides	Metabolic Disease
Palmitoyl hexapeptide-14(Palmitoyl hexapeptide-6)isa bioactive peptide withanti-inflammatoryeffect and has been reported used as a cosmetic ingredient .

HY-P4846

Ac-Pro-Gly-Pro-OH	CXCR	Inflammation/Immunology
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis .

HY-149205

CXJ-2	PI3K ERK	Inflammation/Immunology
CXJ-2 is a cyclic peptide, and exhibits moderate affinity toward elastin derived peptides (EDPs). CXJ-2 exhibits potent activities to inhibit the *PI3K/ERK* pathway and decrease hepatic stellate cell proliferation and migration. CXJ-2 possesses potent antifibrotic efficacy .

HY-13948

Angiotensin II human Maximum Cited Publications 93 Publications Verification Angiotensin II; Ang II; DRVYIHPF	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway ^[3] .

HY-13948A

Angiotensin II human acetate Maximum Cited Publications 93 Publications Verification Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway ^[3] .

HY-13948B

Angiotensin II human TFA Maximum Cited Publications 93 Publications Verification Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway ^[3] .

Cat. No.	Product Name	Target	Research Area

HY-P99644

Glenzocimab ACT017	Inhibitory Antibodies	Cardiovascular Disease
Glenzocimab (ACT017) is a Fab fragment of humanized anti-GPVI monoclonal antibody. Glenzocimab inhibits collagen-induced platelet aggregation. Glenzocimab has the potential for the research of acute ischemic stroke .

HY-P990251

*Anti-Human/Mouse denatured collagen* type-I Antibody (XL313)**	Inhibitory Antibodies	Others
Anti-Human/Mouse denatured collagen type-I Antibody (XL313) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to human/mouse denatured collagen type-I.

Species:	Human (18) Rhesus Macaque (1) Mouse (3) Rat (2) Bovine (1)
Tag:	His (19) Tag Free (2) Avi (1) GST (1) Fc (3)
Source:	HEK293 (18) E. coli Cell-free (1) P. pastoris (2) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P7009

	Collagen Alpha-1(XVIII) Chain/Endostatin Protein, Human (P.pastoris) rHuEndostatin; collagen alpha-1(XV) chain	Human	P. pastoris
	Endostatin Protein, Human (P.pastoris) is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion.

HY-P702615

Collagen XV alpha 1/COL15A1 Protein, Human (His)

collagen alpha-1(XV) chain; COL15A1; collagen Type XV Alpha 1 Chain
Human E. coli Cell-free

HY-P72148

	COL4A3 Protein, Human (His) Alpha 3 type IV collagen; Alpha3 type IV collagen; CO4A3_HUMAN; COL4A 3; Col4a3; collagen alpha 3IV; chain; collagen IV alpha 3 polypeptide; collagen type IV alpha 3 Goodpasture antigen; ; collagen type IV alpha 3; collagen type IV alpha 3 chain; Goodpasture antigen; OTTHUMP00000195044; Tumstatin	Human	E. coli
	The COL4A3 protein is an important type IV collagen component that, together with laminin, proteoglycans, and nestin/nesidin, plays a role in forming the "chicken wire" network structure in the glomerular basement membrane (GBM). Key role. Its cleavage product tumstatin is derived from the NC1 domain of collagen α 3(IV) and has dual anti-angiogenic and anti-tumor cell activities. COL4A3 Protein, Human (His) is the recombinant human-derived COL4A3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of COL4A3 Protein, Human (His) is 242 a.a., with molecular weight of ~30.6 kDa.

HY-P70347

	Collagen alpha-1(XVIII) chain/COL18A1 Protein, Mouse (HEK293, His) rMucollagen Alpha-1(XVIII) Chain/Endostatin, His; antiangiogenic agent; COL18A1; collagen alpha-1(XVIII)chain; collagen; type XVIII; Endostatin	Mouse	HEK293
	The COL18A1 protein may play a key role in shaping retinal structure and promoting neural tube closure. Its involvement extends to the regulation of extracellular matrix-dependent motility and morphogenesis of endothelial and non-endothelial cells. Collagen alpha-1 (XVIII) chain/COL18A1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Collagen alpha-1(XVIII) chain/COL18A1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collagen alpha-1 (XVIII) chain/COL18A1 Protein, Mouse (HEK293, His) is 184 a.a., with molecular weight of ~18.0 kDa.

HY-P75333

	Collagen alpha-1(II) chain/COL2A1 Protein, Human (HEK293, His) collagen alpha-1(II) chain; Chondrocalcin; COL2A1	Human	HEK293
	COL2A1, encoding the alpha-1(II) chain of type II collagen, is specific to cartilaginous tissues, essential for embryonic skeletal development, linear growth, and cartilage resilience against compressive forces. As a fundamental component of homotrimers, COL2A1 maintains the structural integrity and function of cartilage, crucial for skeletal form and function during development and in resisting mechanical stress. Collagen alpha-1 (II) chain/COL2A1 Protein, Human (HEK293, His) is the recombinant human-derived Collagen alpha-1(II) chain/COL2A1 protein, expressed by HEK293 , with N-His labeled tag. The total length of Collagen alpha-1 (II) chain/COL2A1 Protein, Human (HEK293, His) is 246 a.a., with molecular weight of ~32-37 kDa.

HY-P70018

	Collagen alpha-1(VIII) chain/COL8A1 Protein, Human (HEK293, His) rHucollagen alpha-1(VIII) chain/COL8A1, His ; collagen Alpha-1(VIII) Chain; Endothelial collagen; Vastatin; COL8A1; C3orf7	Human	HEK293
	Collagen alpha-1(VIII) chain (COL8A1) is an important macromolecular component of Descemet membrane formation and the endothelial lining of blood vessels. COL8A1 is critical for vascular smooth muscle cell migration and proliferation, suggesting its importance in maintaining the structural integrity of the vessel wall, particularly in atherogenesis. Collagen alpha-1 (VIII) chain/COL8A1 Protein, Human (HEK293, His) is the recombinant human-derived Collagen alpha-1(VIII) chain/COL8A1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collagen alpha-1 (VIII) chain/COL8A1 Protein, Human (HEK293, His) is 717 a.a., with molecular weight of ~54.55 & 78.13 kDa, respectively.

HY-P7886

	Collagen alpha-1(III) chain/COL3A Protein, Mouse (HEK293, His) rMucollagen alpha-1(III) chain/COL3A, His; collagen alpha-1(III) chain; Col3a1	Mouse	HEK293
	COL3A protein, also known as collagen α-1(III) chain, is an important component of type III collagen and is widely distributed along with type I collagen in most soft connective tissues. In addition to its structural role, COL3A is also involved in the regulation of cortical development. Collagen alpha-1 (III) chain/COL3A Protein, Mouse (HEK293, His) is the recombinant mouse-derived Collagen alpha-1(III) chain/COL3A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collagen alpha-1 (III) chain/COL3A Protein, Mouse (HEK293, His) is 1065 a.a., with molecular weight of ~130.0 kDa.

HY-P72147

	COL4A2 Protein, Human (His) 1 Publications Verification Canstatin; CO4A2_HUMAN; COL4A 2; Col4a2; collagen alpha 2IV; chain; collagen; type IV; alpha 2	Human	E. coli
	COL4A2 protein is a key type IV collagen element that forms the main structural component of the glomerular basement membrane (GBM), forming a unique "chicken wire" network structure with laminin, proteoglycans and nestin/nesidin. . Canstatin is a cleavage product of the NC1 domain of collagen α 2(IV) and has potent anti-angiogenic and anti-tumor activities. COL4A2 Protein, Human (His) is the recombinant human-derived COL4A2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of COL4A2 Protein, Human (His) is 220 a.a., with molecular weight of ~28.3 kDa.

HY-P75684

	COL6A3 Protein, Human (HEK293) collagen alpha-3(VI) chain; COL6A3	Human	HEK293
	COL6A3 protein is an important component of type VI collagen and has the function of a cell-binding protein. Collagen VI trimers are composed of three distinct chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI), alpha-5(VI), or alpha-6(VI). COL6A3 Protein, Human (HEK293) is the recombinant human-derived COL6A3 protein, expressed by HEK293 , with tag free. The total length of COL6A3 Protein, Human (HEK293) is 77 a.a., with molecular weight of ~8.5 kDa.

HY-P70009

	Collagen alpha-1(IX) chain/COL9A1 Protein, Human (HEK293, His) rHucollagen alpha-1(IX) chain/COL9A1, His; collagen alpha-1(IX) chain; DJ149L1.1.2; EDM6; MED; STL4	Human	HEK293
	Collagen alpha-1(IX) chain (COL9A1) is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage and a structural component of vitreous in the eye. Synthesis of COL9A1 chain is essential for assembly of type IX collagen molecules, and mutations of COL9A1 are associated with osteoarthritis in humans, multiple epiphyseal dysplasia, and Stickler syndrome. Collagen alpha-1 (IX) chain/COL9A1 Protein, Human (HEK293, His) is the recombinant human-derived Collagen alpha-1(IX) chain/COL9A1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collagen alpha-1 (IX) chain/COL9A1 Protein, Human (HEK293, His) is 575 a.a., with molecular weight of 38-50 kDa.

HY-P75685

	COL6A3 Protein, Human (HEK293, His) collagen alpha-3(VI) chain; COL6A3	Human	HEK293
	COL6A3 protein is an important component of type VI collagen and has the function of a cell-binding protein. Collagen VI trimers are composed of three distinct chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI), alpha-5(VI), or alpha-6(VI). COL6A3 Protein, Human (HEK293, His) is the recombinant human-derived COL6A3 protein, expressed by HEK293 , with N-His labeled tag. The total length of COL6A3 Protein, Human (HEK293, His) is 77 a.a., with molecular weight of ~13.3 kDa.

HY-P70094

	COL21A1 Protein, Human (HEK293, His) rHucollagen alpha-1(XXI) chain/COL21A1, His ; COL21A1; collagen, type XXI, alpha 1; collagen alpha-1(XXI) chain; alpha 1 type XXI collagen; FP633; COLA1L; dJ708F5.1; dJ682J15.1; FLJ39125; FLJ44623; MGC26619; DKFZp564B052	Human	HEK293
	COL21A1 Protein is a member of the fibre-associated collagen interrupt helix (FACIT) family. COL21A1 Protein is a secreted protein widely present in a variety of tissues. COL21A1 Protein may contribute to the extracellular matrix assembly of vascular networks during angiogenesis. COL21A1 Protein, Human (HEK293, His) is the recombinant human-derived COL21A1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of COL21A1 Protein, Human (HEK293, His) is 935 a.a., with molecular weight of 115-125 & 220 kDa, respectively.

HY-P76930

	Ficolin-1 Protein, Human (HEK293, His) Ficolin-1; collagen/fibrinogen domain-containing protein 1; Ficolin-A; FCNM	Human	HEK293
	IFN-β protein is a recombinant protein that does not use any animal-derived components in its production. It is used in biomedical research and drug manufacturing as a therapeutic agent for a variety of diseases, including multiple sclerosis. Ficolin-1 Protein, Human (HEK293, His) is the recombinant human-derived Ficolin-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Ficolin-1 Protein, Human (HEK293, His) is 297 a.a., with molecular weight of 33-38 kDa.

HY-P76299

	CTHRC1 Protein, Rat (HEK293, His) collagen triple helix repeat-containing protein 1; Protein NMTC1; CTHRC1	Rat	HEK293
	CTHRC1, with predicted Wnt-protein and frizzled binding activity, influences cell migration. Located in the extracellular matrix, this protein, implicated in Barrett's esophagus, exhibits biased expression in lung (RPKM 46.1) and muscle (RPKM 36.6), suggesting its role in diverse physiological processes across tissues. CTHRC1 Protein, Rat (HEK293, His) is the recombinant rat-derived CTHRC1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CTHRC1 Protein, Rat (HEK293, His) is 230 a.a., with molecular weight of ~27 KDa.

HY-P75683

	COL4A3 Protein, Rat (HEK293, Fc) collagen alpha-3(IV) chain; Goodpasture antigen; Tumstatin; COL4A3	Rat	HEK293
	The COL4A3 protein is a key type IV collagen component that forms the major structural element of the glomerular basement membrane (GBM). It collaborates with laminin, proteoglycans, and nestin/nesidin to create a "chicken wire" network that is critical for maintaining the structural integrity of the GBM. COL4A3 Protein, Rat (HEK293, Fc) is the recombinant rat-derived COL4A3 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of COL4A3 Protein, Rat (HEK293, Fc) is 245 a.a., with molecular weight of ~59 kDa.

HY-P77368

	Ficolin-1 Protein, Rhesus Macaque (HEK293, Fc) collagen/fibrinogen domain-containing protein 1; Ficolin-A; M-ficolin; FCN1; FCNM	Rhesus Macaque	HEK293
	Ficolin-1 functions locally after inflammatory lesions in monocyte, macrophage, and granulocyte secretion, and is also present in serum, suggesting that it may play a role in systemic immunity. Ficolins recognize and bind to pathogens, leading to neutralization and conditioning, which subsequently activates the complement lectin pathway. Ficolin-1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Ficolin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Ficolin-1 Protein, Rhesus Macaque (HEK293, Fc) is 297 a.a., with molecular weight of ~59.1 KDa.

HY-P70092

	CTHRC1 Protein, Human (HEK293, His) rHucollagen triple helix repeat-containing protein 1/CTHRC1, His; collagen triple helix repeat-containing protein 1; Protein NMTC1; CTHRC1	Human	HEK293
	CTHRC1 Protein, Human (HEK293, His) is a negative regulator of collagen matrix deposition. CTHRC1, a secreted 28-kDa protein, is a glycosylated protein with a signal sequence.

HY-P70180

	GPVI Protein, Mouse (HEK293, His) rMuGlycoprotein 6 (Platelet)/GPVI, His ; Glycoprotein 6; glycoprotein VI (platelet); GP6; GPIV; GPVI; GPVIplatelet collagen receptor; MGC138168; platelet glycoprotein VI	Mouse	HEK293
	GPVI Protein is a platelet membrane protein with a molecular weight of ~62 kDa that is a physiological collagen receptor. GPVI is present as a complex with the homodimeric Fc receptor y-chain. GPVI must form such a dimeric complex to exhibit high affinity binding to collagen. The GPVI-induced activation mechanism is initiated by tyrosine phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of the FcR gamma-chain, and then this signal is transduced to many related proteins, mainly by tyrosine phosphorylation. Interaction of platelets with collagen via the receptor GPVI results in platelet activation and adhesion. GPVI Protein, Mouse (HEK293, His) is the recombinant mouse-derived GPVI protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GPVI Protein, Mouse (HEK293, His) is 244 a.a., with molecular weight of 40-60 kDa.

HY-P70004

	CD36 Protein, Human (HEK293, Fc ) rHuPlatelet glycoprotein 4/CD36, Fc; Fatty acid translocase; Glycoprotein IIIb; FATCHDS7; Leukocyte differentiation antigen CD36; PAS IV; Platelet collagen receptor; SCARB3; Thrombospondin receptor; CD36	Human	HEK293
	CD36 is a multifunctional glycoprotein that serves as a receptor for a variety of ligands, including thrombospondin and oxidized low-density lipoprotein. Ligand induces CD36 clusters, initiating signal transduction and internalization. CD36 Protein, Human (HEK293, Fc ) is the recombinant human-derived CD36 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD36 Protein, Human (HEK293, Fc ) is 410 a.a., with molecular weight of 90-130 kDa.

HY-P71827

	Adiponectin/Acrp30 Protein, Bovine (P.pastoris, His) ADIPOQ; ACRP30Adipocyte complement-related 30kDa protein; ACRP30; Adipocyte; C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1	Bovine	P. pastoris
	Adiponectin/Acrp30 Protein, Bovine (P.pastoris, His) can increase cell sensitivity to insulin and can be used as a potential protein for diabetic tendinopathy research.

HY-P71444

	COL4A1 Protein, Human (GST) Arresten; BSVD; COL4A1; COL4A1 NC1 domain; COL4A2; COL4A3; COL4A4; COL4A5; collagen alpha-1(IV) chain	Human	E. coli
	COL4A1 protein is an important type IV collagen component that forms the main structural framework of the glomerular basement membrane (GBM) with a unique "chicken wire" mesh structure. It cooperates with laminin, proteoglycans and nestin/nesidin to maintain the structural integrity of GBM. COL4A1 Protein, Human (GST) is the recombinant human-derived COL4A1 protein, expressed by E. coli , with N-GST labeled tag. The total length of COL4A1 Protein, Human (GST) is 138 a.a., with molecular weight of ~ 42 kDa.

HY-P78409

	CD36 Protein, Human (HEK293, His-Avi) CD36 antigen; CD36; collagen R; FAT; FATCHDS7; Glycoprotein IIIb; GPIIIb; GPIV; PAS IV; PAS-4; SCARB3; SRB3; SR-B3; Thrombospondin R; BDPLT10; CHDS7; GP3B	Human	HEK293
	CD36, a versatile glycoprotein, acts as a receptor for diverse ligands, including thrombospondin and oxidized LDL. Ligands induce CD36 clusters, initiating signal transduction and internalization. Cellular responses influence angiogenesis, inflammation, fatty acid metabolism, taste, and gut fat absorption. CD36 facilitates fatty acid transport, impacting muscle utilization and adipose storage. Mechanistically, fatty acid binding activates LYN kinase, leading to CD36 depalmitoylation and endocytosis. In the small intestine, CD36 aids dietary absorption via MAPK1/3 signaling. It also regulates oral fat perception, hypothalamic function, and contributes to antiangiogenic and inflammatory effects. Additionally, CD36 selectively senses microbial lipopeptides, triggering NF-kappa-B-dependent responses via TLR2:TLR6 heterodimer signaling. In infections, CD36 mediates cytoadherence of Plasmodium falciparum-infected erythrocytes and particle internalization. CD36 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD36 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of CD36 Protein, Human (HEK293, His-Avi) is 410 a.a., with molecular weight of 70-80 kDa.

HY-P70504

	Adiponectin/Acrp30 Protein, Human (HEK293, His) 1 Publications Verification Adiponectin; 30 kDa Adipocyte Complement-Related Protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte; C1q and collagen Domain-Containing Protein; Adipose Most Abundant Gene Transcript 1 Protein; apM-1; Gelatin-Binding Protein; ADIPOQ; ACDC; ACRP3	Human	HEK293
	Adiponectin/Acrp30 Protein, Human (HEK293, His) could increase cell sensitivity to insulin and can be used as a potential protein for treating diabetic tendinopathy.

HY-P71298

	Serpin H1 Protein, Human (HEK293, His) Serpin H1; 47 kDa Heat Shock Protein; Arsenic-Transactivated Protein 3; AsTP3; Cell Proliferation-Inducing Gene 14 Protein; collagen-Binding Protein; Colligin; Rheumatoid Arthritis-Related Antigen RA-A47; SERPINH1; CBP1; CBP2; HSP47; SERPINH2	Human	HEK293
	Serpin H1 protein exhibits a specific affinity for collagen, indicating its role as a chaperone in the biosynthetic pathway of collagen. This suggests its potential contribution to collagen synthesis, emphasizing its importance in maintaining tissue integrity and modulating cellular responses related to collagen metabolism. Serpin H1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin H1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin H1 Protein, Human (HEK293, His) is 400 a.a., with molecular weight of ~51.0 kDa.

HY-P71917

	P4HB Protein, Human (His) Cellular thyroid hormone binding protein; Cellular thyroid hormone-binding protein; collagen prolyl 4 hydroxylase beta; Disulphide Isomerase; DSI; EC 5.3.4.1; ER protein 59; ERBA2L; ERp59; GIT; P4HB; P4Hbeta; p55; PDI; PDIA1; PDIA1_HUMAN; PDIR; PHDB; PO4DB; PO4HB; PROHB; Protocollagen hydroxylase; Thbp;	Human	E. coli
	The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (His) is the recombinant human-derived P4HB protein, expressed by E. coli , with N-6*His labeled tag. The total length of P4HB Protein, Human (His) is 490 a.a., with molecular weight of ~56 kDa.

Cat. No.	Product Name	Chemical Structure

HY-B0166S8

L-Ascorbic acid-13C6-1

L-Ascorbic acid- ¹³C₆-1 (L-Ascorbate-1; Vitamin C- ¹³C₆-1) is a ¹³C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[3] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166S3

L-Ascorbic acid-13C-2
L-Ascorbic acid- ¹³C-2 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-40136S

cis-4-Hydroxy-L-proline-d3

cis-4-Hydroxy-L-proline-d₃ is the deuterium labeled cis-4-Hydroxy-L-proline. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[1][2][3][4].

HY-B0166S2

L-Ascorbic acid-13C-1
L-Ascorbic acid- ¹³C-1 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S4

L-Ascorbic acid-13C-3
L-Ascorbic acid- ¹³C-3 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S

L-Ascorbic acid-13C6

L-Ascorbic acid- ¹³C₆ is the ¹³C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

HY-B0166S1

L-Ascorbic acid-13C

L-Ascorbic acid- ¹³C is the ¹³C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

Cat. No.	Product Name	Application	Reactivity

HY-P80627

Collagen I alpha 2 Antibody collagen alpha-2(I) chain (Alpha-2 type I collagen)	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
Collagen I alpha 2 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 129 kDa, targeting to Collagen I alpha 2. It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P81047

Collagen II Antibody collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1(II); type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; collagen alpha 1(II) chain precursor; collagen II alpha 1 polypeptide; collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital); MGC131516; SEDC; collagen alpha-1(II) chain; Alpha-1 type II collagen; CO2A1_HUMAN.; collagenII;	WB, ELISA, IHC-P, IF	Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig
Collagen II Antibody is an unconjugated, approximately 117 KDa, rabbit-derived, anti-Collagen II polyclonal antibody. Collagen II Antibody can be used for: WB, ELISA, IHC-P, IF expriments in human, mouse, rat, chicken, dog, pig, cow, rabbit, guinea pig background without labeling.

HY-P81227

Collagen I Antibody collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; collagen I alpha 1 polypeptide; collagen I alpha 2 polypeptide; collagen Of Skin Tendon And Bone; collagen Type 1; collagen type I alpha 1; collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat, Rabbit(predicted: Chicken, Dog, Cow, Sheep)
Collagen I Antibody is an unconjugated, approximately 130 kDa, rabbit-derived, anti-Collagen I polyclonal antibody. Collagen I Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, rabbit, and predicted: chicken, dog, cow, sheep background without labeling.

HY-P81201

Collagen IV Antibody Arresten; Canstatin; COL4A1; HANAC; ICH; POREN1; collagen Alpha 1(IV) Chain; collagen IV Alpha 1 Polypeptide; collagen Of Basement Membrane Alpha 1 Chain; collagen Of Basement Membrane Alpha 2 Chain; collagen Type IV Alpha 1; DKFZp686I14213; FLJ22259; collagen alpha-1(IV) chain preproprotein; collagen alpha-1(IV) chain preproprotein; Col4a1 protein; collagen of basement membrane, alpha-1 chain; collagen IV, alpha-1 polypeptide; collagen alpha-1(IV) chain; COL4A1 NC1 domain; CO4A1_HUMAN; collagen Ⅳ; collagen Type Ⅳ.	ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit)
Collagen IV Antibody is an unconjugated, approximately 165 kDa, rabbit-derived, anti-Collagen IV polyclonal antibody. Collagen IV Antibody can be used for: ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: chicken, dog, pig, cow, horse, rabbit background without labeling.

HY-P81101

Collagen III Antibody COL 3A1; COL3A1; collagen alpha 1(III) chain; collagen III alpha 1 chain precursor; collagen III alpha 1 polypeptide; collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant); collagen type III alpha 1; collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; Fetal collagen; Type III collagen; CO3A1_HUMAN; collagen alpha-1(III) chain; Type III collagen; type III preprocollagen alpha 1 chain.	WB; ELISA; IHC-P; IHC-F; IF	Human, Dog, Rabbit(predicted: Mouse, Rat, Chicken, Cow)
Collagen III Antibody is an unconjugated, approximately 117 kDa, rabbit-derived, anti-Collagen III polyclonal antibody. Collagen III Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, dog, rabbit, and predicted: mouse, rat, chicken, cow background without labeling.

HY-P83014

Collagen XVII alpha 1 Antibody (YA2759)

BP180; BPA 2; BPAG2; COL17A1; collagen 17; collagenXVII; LAD1
WB, IHC-P, ICC/IF, IP Human, Mouse, Rat

HY-P81102

Collagen X Antibody collagen type X; Col10a 1; collagen alpha 1(X) chain; collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia); collagen type X alpha 1; collagen X alpha 1 polypeptide; collagenX; fa66d11; fb10c08; OTTHUMP00000040411; Procollagen type X alpha 1; Schmid metaphyseal chondrodysplasia; wu:fa66d11; wu:fb10c08; COAA1_HUMAN; COL10A1; collagen alpha-1(X) chain; collagen alpha-1(X) chain precursor; Schmid metaphyseal chondrodysplasia; collagen X, alpha-1 polypeptide.	WB; ELISA; IHC-P; IHC-F; IF	Mouse, Rat(predicted: Human, Chicken, Dog, Cow, Rabbit)
Collagen X Antibody is an unconjugated, approximately 73 kDa, rabbit-derived, anti-Collagen X polyclonal antibody. Collagen X Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in mouse, rat, and predicted: human, chicken, dog, cow, rabbit background without labeling.

HY-P81048

Collagen VI Antibody (YA893) Alpha 1 (VI) chain (61 AA) antibody; CO6A1_HUMAN antibody; COL6A1 antibody; collagen alpha-1(VI) chain antibody; collagen type VI alpha 1 antibody; collagen VI alpha 1 polypeptide antibody; collagen VI antibody; Human mRNA for collagen VI alpha 2 C terminal globular domain antibody; OPLL antibody; PP3610 antibody	WB, IF-Cell, IF-Tissue, IHC-P	Human, Mouse, Rat
Collagen VI Antibody (YA893) is an unconjugated, approximately 109 kDa, rabbit-derived, anti-Collagen VI (YA893) monoclonal antibody. Collagen VI Antibody (YA893) can be used for: WB, IF-Cell, IF-Tissue, IHC-P expriments in human, mouse, rat background without labeling.

HY-P82231

Collagen XI alpha 1 Antibody (YA1976)

COL11A1; COLL6; collagen alpha-1(XI) chain
WB Human
HY-P82837

Collagen X alpha 1 Antibody (YA2582)

collagenX; COL10A1; COAA1; collagen type X alpha 1
WB Human, Mouse, Rat

HY-P82892

Collagen VI alpha 1/2/3 Antibody (YA2637) Alpha 1 (VI) chain (61 AA); COL6A1; COL6A2; COL6A3; collagen alpha 2(VI) chain; collagen alpha 3(VI) chain; OPLL; PP3610	WB, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P82788

Collagen VI alpha 1 Antibody (YA2533)

OPLL; BTHLM1; UCHMD1
WB, IHC-F, IHC-P, ICC/IF Human

HY-P80004

Adiponectin Antibody 30 kDa adipocyte complement related protein; ACDC; ACRP 30; ACRP30; ADIPO_HUMAN; Adipocyte; AdipoQ; Adipose most abundant gene transcript 1; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM 1; apM-1; ApM1; C1q and collagen domain-containing protein; GBP 28; GBP28; Gelatin binding protein; Gelatin binding protein 28; Gelatin-binding protein.	WB, ICC, IHC-P	Mouse
Adiponectin Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 27 kDa, targeting to Adiponectin. It can be used for WB,ICC,IHC-P assays with tag free, in the background of Mouse.

HY-P83362

Integrin alpha 2 Antibody (YA3107) ITGA2; CD49B; Integrin alpha-2; CD49 antigen-like family member B; collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P81793

CD36 Antibody (YA1538) CD36; GP3B; GP4; Platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36	WB, IHC-P, IP	Human, Mouse, Rat

Cat. No.	Product Name		Classification

HY-100495

FT011 1 Publications Verification		Alkynes
FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis . FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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